|IDEA BY:||何东明EastBright OrientalTowerHo||LOCATION:||Other||CATEGORY:||Science/Medical|
|IDEA BY:||何东明EastBright OrientalTowerHo|
SI=F(η+ε+T+pH+Ve+Ψ),SI=SIo+ΔSI,SI∈[SI1,SI2], η : viscosity coefficient of the cellular condition, ε :dielecric constant ,T :temperature, pH : pH in cell ,Ve :energy metabolic speed, Ψ :oxidation-reduction potential SI∝1/Sentropy.SI be the SystemIndex for drug selection.when the conditions change so sharply, the interaction of the molecules can change as a result—no interaction or new interaction. The researchers always assume that the signal molecules interaction will stay the same if there are not the genetic or epigenetic changes of the moleculars，yet it may be not all the same case. One exmaple is the cancer, researches show that the cellular physicochemical conditions of the cancer cells change a lot compared to the normal cells,so it is probably that there are some new molecules interaction .This can explain why many cancer drugs targeted one or a few important life molecules do not work well or appear many problems.2.StemCells have the suitable SI can follow SI program in development to form the heart or correspond organ. If not for the severely change ,the cell will go on its SI change program in the way as the development process.So,the CSC has a special SI and can differentiate into many different cancer cells.