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ENTRY TITLE

Rapid diagnosis of breast cancer
IDEA BY: Joshua Moss LOCATION: Canada CATEGORY: Science/Medical

ENTRY TITLE

Rapid diagnosis of breast cancer
IDEA BY: Joshua Moss
LOCATION: Canada
CATEGORY: Science/Medical

ENTRY DESCRIPTION

It currently takes several weeks to diagnosis breast cancer. I have an idea for a test which can allow diagnosis in a few hours.

When a woman is suspected to have breast cancer, based on an abnormal mammography, she will usually undergo a biopsy to determine whether the abnormality is cancer or something else. From the time the biopsy is taken until the patient receives a diagnosis generally takes several weeks, while the sample taken is prepared and analyzed by a pathologist. DNA methylation is a chemical modification to DNA which is responsible for regulating activity of genes. It is well established that in cancer, many regions of the genome become methylated. Therefore, analysis of the DNA methylation of a breast biopsy can allow the determination of whether or not it contains cancerous cells. Such an analysis can be done for a few dollars per sample, and would take less than a day. My idea is to develop a kit which allows for the analysis of DNA methylation at key regions of the genome in breast biopsy samples. This will allow for extremely rapid, accurate and unbiased diagnosis of breast cancer. Such an invention would save valuable hospital resources and allow tremendous improvement to patient care, as patients who require treatment will be able to receive it much sooner, greatly increasing their chance of beating the disease.